2018-07-16 12:39:092025-05-22 12:24:06

locus

BSU33000

BSU_33000

geneLength

1374

1377

outlinks

bsu

BSU33000

BSU_33000

Gene

Coordinates

3,384,070 → 3,385,446

3,384,070 3,385,446

The protein

Protein family

peptidase S1B family (according to Swiss-Prot)

Peptidase S1C family (with [[protein|HtrA]] and [[protein|HtrC]], according to UniProt)

The protein

[SW|Localization]

cell membrane (according to Swiss-Prot)

randomly distributed in foci throughout the cell surface [Pubmed|22307758]

cell membrane (according to UniProt)

randomly distributed in foci throughout the cell surface [Pubmed|22307758]

Biological materials

Mutant

MGNA-B207 (yvtA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1206 NBRP B. subtilis, Japan]

BKE33000 (Δ[[gene|htrB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE33000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTCTTACACTCCTTTA, downstream forward: _UP4_TAAGAAAAAACAAAAAGCTG

BKK33000 (Δ[[gene|htrB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK33000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTCTTACACTCCTTTA, downstream forward: _UP4_TAAGAAAAAACAAAAAGCTG

MGNA-B207 (yvtA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1206 NBRP B. subtilis, Japan]

BKE33000 ([[gene|htrB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE33000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTCTTACACTCCTTTA, downstream forward: _UP4_TAAGAAAAAACAAAAAGCTG

BKK33000 ([[gene|htrB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK33000 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTCTTACACTCCTTTA, downstream forward: _UP4_TAAGAAAAAACAAAAAGCTG

References

Reviews

22688815, 21326199, 25212246

22688815, 21326199, 25212246, 31001739

References

Original publications

17600057, 22307758, 12270824, 22092710, 24362423, 24115457, 11133960, 21532594

17600057, 22307758, 12270824, 22092710, 24362423, 24115457, 11133960, 21532594, 32111210

The protein

Catalyzed reaction/ biological activity

Acts on substrates that are at least partially unfolded. The cleavage site P1 residue is normally between a pair of hydrophobic residues, such as Val-|-Val (according to UniProt)

The protein

Paralogous protein(s)

[[this]]

The protein

[SW|Domains]

cytoplasmic domain (aa 1 - 71) (according to UniProt)

transmembrane helix (aa 72 - 92) (according to UniProt)

extracellular domain (aa 93 - 458) (according to UniProt)

[SW|PDZ domain] (aa 350- 449) (according to UniProt)